Martini perspective

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Last Updated: Saturday, 09 November 2013 13:11
A review of the Martini force field has appeared, with an overview of one decade of Martini applications, discussion of its limitations, and an outlook on future developments:
S.J. Marrink & D.P. Tieleman, "Perspective on the Martini model",  Chem. Soc. Rev., 42:6801-6822, 2013. Open access

Glycolipids dominate the world

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Last Updated: Monday, 15 December 2014 11:47

Martini glycolipid force field releasedglycoworld

C.A. Lopez, Z. Sovova, F.J. van Eerden, A.H. de Vries, S.J. Marrink.
Martini force field parameters for glycolipids.
J. Chem. Theory Comput., 9:1694–1708, 2013. DOI:10.1021/ct3009655
 

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Martini 2.2

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Last Updated: Saturday, 09 November 2013 13:13

 

Try out now! Martini 2.2: Improved parameters for the protein force field

D.H. de Jong, G. Singh, W.F.D. Bennett, C. Arnarez, T.A. Wassenaar, L.V. Schäfer, X. Periole, D.P. Tieleman, S.J. Marrink
Improved Parameters For The Martini Coarse-Grained Protein Force Field, J. Chem. Th. Comp, 9:687–697, 2013. DOI:10.1021/ct300646g

martini22-toc
Curious? Go here for downloading the Martinize script which now features a beta release of Martini 2.2. Any feedback is appreciated so we can further improve the model.

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Dimerization of GPCRs

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Last Updated: Saturday, 09 November 2013 13:13
 

First report on the free energy surface of membrane protein dimerization

gcpr-dimer
 
X. Periole, A.M. Knepp, T.P. Sakmar, S.J. Marrink, T. Huber.
Structural determinants of the supra-molecular organization of
G protein-coupled receptors in bilayers.
 
JACS, 134 (26), pp 10959–10965. abstract

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Martinize

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Last Updated: Thursday, 22 August 2013 14:07

A new script to generate both structure and topology files for coarse grain proteins has been released: Martinize.py. Generating input files for a Martini simulation from an atomistic structure takes only one step!

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