New PhD and postdoc positions available
- Last Updated: Thursday, 07 December 2017 08:38
A number of PhD/postdoc positions are available in our group within the BaSyc consortium. BaSyc has the ambitious aim to build a synthetic cell that can sustain itself, grow, replicate, and divide.
For more information, and how to apply, see https://www.rug.nl/research/
Merry Christmas and a happy new year!
- Last Updated: Thursday, 14 December 2017 20:29
We would like to wish you all a merry Christmas and a happy new year, may you all have a blast!
If you feel bored during the Xmas break, please provide us with movies of exploding Martini-bead snowmen, Santaclaus, or other stuff you'ld like to see blasted.
Who says Martini is too sticky ??
- Last Updated: Wednesday, 29 November 2017 12:47
Adding a lipid to your protein will be a piece of cake from now on.
Yoav Atsmon-Raz, and D. Peter Tieleman. Parameterization of Palmitoylated Cysteine, Farnesylated Cysteine, Geranylgeranylated Cysteine and Myristoylated Glycine for the Martini Force Field J. Phys. Chem. B,16 Nov 2017. article
The adapted martinize.py they used for adding the tails.
Brain plasma membrane
- Last Updated: Wednesday, 22 November 2017 08:28
Lipid organization and dynamics of biologically complex plasma membranes; comparison of on idealized brain to an average membrane mixture.
H.I. Ingólfsson, T.S. Carpenter, H. Bhatia, P.T. Bremer, S.J. Marrink, F.C. Lightstone. Computational Lipidomics of the Neuronal Plasma Membrane. Biophys. J. 113:2271–2280, 2017. open access
- Last Updated: Thursday, 16 November 2017 19:50
Current force fields tend to overstabilize protein-protein interactions, and Martini is no exception. A recent paper by the Vattulainen group shows the stickiness is also haunting membrane embedded proteins:
M. Javanainen, H. Martinez-Seara, I. Vattulainen. PLoS ONE 12:e0187936, 2017. https://doi.org/10.1371/journal.pone.0187936
We are working hard to improve the protein-protein interactions in the forthcoming Martini 3.0 force field, featuring a thoroughly recalibrated interaction matrix, with a planned release early 2018.